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Intensive BP control may reduce the risk of mild cognitive impairment


Treatment of hypertension to systolic blood pressure (SBP) levels of less than 120 mm Hg did not result in a lower incidence of dementia, but did significantly reduce the risk of mild cognitive impairment compared with less-intensive BP control to SBP levels of less than 140 mm Hg, according to data from the SPRINT MIND trial published in JAMA.


The SPRINT MIND Investigators for the SPRINT Research Group, et al. Effect of intensive vs standard blood pressure control on probable dementia: a randomized clinical trial. JAMA. 2019;321(6):553–61. 

Yaffe K. Prevention of cognitive impairment with intensive systolic blood pressure control. JAMA. 2019;321(6):