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Adverse Effects Can Undermine HAART Adherence

KEY POINT

For highly active antiretroviral therapy (HAART) to control HIV infection, adherence at the 90%–95% level is necessary. Without this type of commitment to medication therapy, drug resistance develops, and virologic failure is common. In addition to helping patients understand the need for adherence and developing systems for managing complicated regimens, pharmacists should focus their clinical activities on recognizing and treating adverse effects of these agents.

SOURCES

Guidelines for using antiretroviral agents among HIV-infected adults and adolescents: recommendations of the Panel on Clinical Practices for Treatment of HIV. MMWR. 2002;51(RR-7).