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Antiretroviral Selection and Adherence: Essential to Long-Term Success

KEY POINT

Once achieved in drug-naive patients, viral suppression can be maintained for several years in patients whose therapy is not interrupted. But two factors are critical in this success: Clinicians must make optimal choices for initial drug therapy, and patients must adhere to the prescribed medications. Two recent studies provide insights into how these dual goals can best be achieved.

SOURCES

Matthews GV et al. Virological suppression at 6 months is related to choice of initial regimen in antiretroviral-naive patients: a cohort study. AIDS. 2002:16:53–61.

Philips AN et al. Durability of HIV-1 viral suppression over 3.3 years with multidrug antiretroviral therapy in previously drug-naive individuals. AIDS. 2001;15:2379–84.