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Treating patients coinfected with HIV and hepatitis poses challenges

KEY POINT

Coinfection with HIV and hepatitis B or C virus (HBV or HCV) is common, and patients’ prognosis is poorer than for either disease alone. Treatment considerations for hepatitis include drug interactions with HIV drugs, risks of hepatotoxicity induced by antiretroviral drugs, and resistance of HIV and/or HBV to antiviral agents. An international panel recently released updated recommendations for treating this coinfection.