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I.V. iron: Serious adverse events in chronic kidney disease


Use of I.V. iron compared with oral iron in patients with chronic kidney disease (CKD) who are not on dialysis was associated with an increased risk of serious cardiovascular events and infections resulting in hospitalizations, according to primary results from the REVOKE study. 


Agarwal R et al. A randomized trial of intravenous and oral iron in chronic kidney disease. Kidney Int. 2015;[Epub ahead of print].

Kidney Disease: Improving Global Outcomes (KDIGO) Anemia Work Group. KDIGO Clinical Practice Guideline for Anemia in Chronic Kidney Disease. Kidney Inter. 2012 (Suppl);2:279–335.

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