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Propranolol use in patients with posttraumatic stress disorder


Administration of propranolol 90 minutes before reactivation of traumatic memories resulted in significant reductions in posttraumatic stress disorder (PTSD) symptoms compared with placebo, according to results of a small study published in the American Journal of Psychiatry.


Brunet A, et al. Reduction of PTSD symptoms with pre-reactivation propranolol therapy:  A randomized controlled trial. Am J Psychiatry. 2018;175(5):427–33.

Friedman MJ. Eradicating traumatic memories: Implications for PTSD treatment. Am J Psychiatry. 2018;175(5):391–2.